Conflicting
Updates on Iron, Chromium, Meal Size, Milk, and L-carnitine
G.
Douglas Andersen, DC, DACBSP, CCN
Volume
15, number 23, 11/3/97, page 24
New studies directly conflict with previous conclusions: iron supplementation
does not increase the risk of heart disease, chromium supplementation
does not increase muscular strength, drinking milk does not cause diabetes.
L-carnitine did help distance runners.
Keeping up with nutrition
is one of the hardest things holistic healers can do. The amount of new
information (and contradictory information) that comes out each month
dwarfs other areas where chiropractors need to keep up. We will start
this month with a few examples of why nutrition can be frustrating.
Iron
A couple of years ago, news was made about iron's role in oxidative stress,
and a study in Finland showed a correlation between heart disease and
high body iron stores. The assumption was that the iron helped catalyze
free radical reactions. In an extensive review, researchers concluded
that high body iron stores do not increase the risk of coronary heart
disease.1
Chromium Picolinate
The last time I wrote about chromium picolinate in this column, it was
a positive study on swimmers showing increased strength and decreased
body fat. This is a study on chromium supplementation using a placebo,
chromium chloride, and chromium picolinate with a controlled 60-minute
strength-straining program five days per week for eight weeks. The researchers
concluded that chromium supplementation did not increase fat loss, muscle
mass, or strength.2
Meal Size
Recent studies have been indicating that eating more small meals results
in lower cholesterol and insulin, and decreasing the risk of cardiovascular
disease. This study compared a nibbling diet (12 meals a day) to a gorging
diet (two meals a day) with similar nutrient and calorie profiles. This
was a short-term study; each group followed the prescribed diet for two
weeks, with a three-week washout. The authors stated that the findings
of this study did not support earlier findings of differences in lipid
profiles with different eating patterns. The only exception was a significant
increase in HDL cholesterol after the gorging meal pattern.3
Milk and Diabetes
A few years ago, there were some studies which indicated there may be
a correlation between the introduction of cow's milk (before 3-4 months
of age) and the development of insulin-dependent diabetes mellitus (IDDM).
Therefore, some physicians have been recommending that families with risk
for insulin-dependent diabetes mellitus avoid introducing milk to their
children. This study of 253 children from families with IDDM who had early
exposure to cow's milk did not reveal any association with IDDM and cow's
milk.4
L-carnitine
L-carnitine has been controversial in its ability to help or hinder athletes.
It has been proven to help patients with angina. It has also been clinically
proven to lower triglycerides in some people. The vast majority of recent
studies on carnitine supplementation on athletes have been negative. This
study, giving marathon athletes 2 gm a day for six weeks resulted in increased
running speed and lowering of heart rates.5
Conclusion
All five of these studies directly contradict the findings of others.
I believe most clinicians just want the truth; unfortunately, predicting
how specific substances can affect human physiology is often very difficult.
One study, whether positive or negative, should make us aware of a problem,
but unless multiple studies can be performed by various independent researchers
who come up with similar conclusions, we should always proceed with caution
and lean toward the recommendation which could do the least harm to a
patient. Using the iron study as an example, until other researchers can
confirm it, I will continue to recommend to patients with a high risk
for cardiovascular disease that they continue to monitor their iron intakes.
References
1. Sempos, Looker, Gillum. Iron and heart disease: the epidemiology data.
Nutrition Review 54(3):73-82, 1996.
2. Lukaski, Bolonchuk, Siders, Milne. Chromium supplementation and resistance
training: Effects on body composition, strength, and trace element status
of men. American Journal of Clinical Nutrition 63:954-965, 1996.
3. Murphy, Chapman, Lovegrove. Meal frequency: does it determine postprandial
lipaemia? European Journal of Clinical Nutrition 50:491-497, 1996.
4. Norris, Beaty, Klingen, Smith, et al. Lack of association between early
exposure to cow's milk, protein, and beta cell autoimmunity. Journal of
the American Medical Association 276: 609-614, 1996; and Schatz, Maclaren.
Cow's milk and insulin-dependent diabetes mellitus: Innocent until proven
guilty. Journal of the American Medical Association 276:647-648, 1996.
5. Swart, Rossouw, Loots, Kruger. Effect of l-carnitine supplementation
on plasma carnitine levels in various performance parameters of male marathon
athletes. Nutrition and Research 17:405-414, 1997.
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2004, G. Douglas Andersen, DC, DACBSP, CCN, 916 E. Imperial Hwy, Brea,
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